deleting mail on device and in Outlook 2010 on Hosted exchange iPhone

I would like to know if I receive an email on my iPhone and want to delete it from the phone without deleting from the server (so it arrives in my inbox or within OWA), can I set the interface to do that?
No.
With my older Blackberry, when I would initiate a delete on the device, I would be offered a choice to delete from handset or delete from handset AND server.
Completely different from a Blackberry, the iPhones Mail app communicates direct with the incoming mail server or server for an email account. RIM provides a dedicated email delivery service for the Blackberry which all email accounts accessed with a Blackberry are routed though. RIMs dedicated email delivery service for the Blackberry includes some features that are not available with an email client that communicates direct with the server such as with an email client on your computer and with the iPhones Mail app.
 MacBook Pro 15" Intel Core 2 Duo/2.53GHz/4GB RAM/500GB HD Mac OS X (10.6.6)  iPod w/Video 30GB,  iPhone 4 32GB